Products

Qualitative

Entrez GeneID

Protein Accession#

Gene Name

CEBPB

Gene Alias

C/EBP-beta, CRP2, IL6DBP, LAP, MGC32080, NF-IL6, TCF5

Gene Description

CCAAT/enhancer binding protein (C/EBP), beta

Omim ID

Gene Ontology

Gene Summary

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. [provided by RefSeq

Other Designations

CCAAT/enhancer binding protein beta|interleukin 6-dependent DNA-binding protein|liver-enriched transcriptional activator protein|nuclear factor of interleukin 6|transcription factor 5