Products

Qualitative

Entrez GeneID

Protein Accession#

Gene Name

ATP1A1

Gene Alias

MGC3285, MGC51750

Gene Description

ATPase, Na+/K+ transporting, alpha 1 polypeptide

Omim ID

Gene Ontology

Gene Summary

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Other Designations

G00-119-711|Na+, K+ ATPase alpha subunit|Na+/K+ -ATPase alpha 1 subunit|Na+/K+ ATPase 1|Na, K-ATPase, alpha-A catalytic polypeptide|Na,K-ATPase alpha-1 subunit|Na,K-ATPase catalytic subunit alpha-A protein|Na/K-ATPase alpha subunit fragment (aa 1-149)|OTT