IAPP (Human) Cell-Based ELISA Kit
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Specification
Product Description
IAPP (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of IAPP expression in cultured cells.
Suitable Sample
Attached Cell, Loosely Attached Cell, Suspension Cell
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Qualitative
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store the kit at 4°C.
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Applications
Qualitative
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Gene Info — IAPP
Entrez GeneID
3375Protein Accession#
P10997Gene Name
IAPP
Gene Alias
AMYLIN, DAP, IAP
Gene Description
islet amyloid polypeptide
Omim ID
147940Gene Ontology
HyperlinkGene Summary
Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. [provided by RefSeq
Other Designations
Islet amyloid polypeptide (diabetes-associated peptide; amylin)
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Interactome
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Disease
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