TNFSF12 (Human) ELISA Kit
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Specification
Product Description
TNFSF12 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human TNFSF12.
Suitable Sample
Cell Lysate, Plasma, Serum
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
16 to 2000 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Expiration Date
Kit expiration is 3 months from date of shipment
Quality Control Testing
Standard Curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store the kit at 4°C.
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Applications
Quantification
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Gene Info — TNFSF12
Entrez GeneID
8742Gene Name
TNFSF12
Gene Alias
APO3L, DR3LG, MGC129581, MGC20669, TWEAK
Gene Description
tumor necrosis factor (ligand) superfamily, member 12
Omim ID
602695Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Some transcripts that skip the last exon of this gene and continue with the second exon of the neighboring TNFSF13 gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq
Other Designations
APO3/DR3 ligand|TNF-related WEAK inducer of apoptosis
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