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C5 (Human) ELISA Kit

  • Catalog # : KA2114
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  • Specification
  • Product Description:
  • C5 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human C5.
  • Calibration Range:
  • 0.313 to 20.00 ng/mL
  • Limit of Detection:
  • 0.1 ng/mL
  • Reactivity:
  • Human, Monkey
  • Storage Instruction:
  • Store components of the kit at 4°C or -20°C as described in the protocol.
  • Suitable Sample:
  • Cell Culture Samples, CSF, Milk, Plasma, Saliva and Serum
  • Sample Volume:
  • 50 uL
  • Label:
  • Biotin-conjugate
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Publication Reference
  • Applications
  • Quantification
  • Application Image
  • Quantification
  • Gene Information
  • Entrez GeneID:
  • 727
  • Gene Name:
  • C5
  • Gene Alias:
  • CPAMD4,FLJ17816,FLJ17822,MGC142298
  • Gene Description:
  • complement component 5
  • Gene Summary:
  • The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000022001,anaphylatoxin C5a analog
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