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ELA2 (Human) ELISA Kit

  • Catalog # : KA1842
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  • Specification
  • Product Description:
  • ELA2 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human ELA2.
  • Calibration Range:
  • 0.156 to 10 ng/mL
  • Limit of Detection:
  • 0.11 ng/mL
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Standard Curve

    QC Testing of KA1842
    The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
  • Storage Instruction:
  • Store components of the kit at 4°C or -20°C as described in the protocol.
  • Suitable Sample:
  • Cell Culture Samples, CSF, Milk, Plasma, Saliva, Serum, Urine
  • Sample Volume:
  • 50 uL
  • Label:
  • Biotin-conjugate
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Quantification
  • Application Image
  • Quantification
  • Gene Information
  • Entrez GeneID:
  • 1991
  • Gene Name:
  • ELA2
  • Gene Alias:
  • GE,HLE,HNE,NE,PMN-E
  • Gene Description:
  • elastase 2, neutrophil
  • Gene Summary:
  • Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins. The product of this gene hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix following the protein's release from activated neutrophils. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is clustered with other serine protease gene family members, azurocidin 1 and proteinase 3 genes, at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq
  • Other Designations:
  • bone marrow serine protease,granulocyte-derived elastase,leukocyte elastase,medullasin,polymorphonuclear elastase
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