CHIT1 (Human) ELISA Kit
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Specification
Product Description
CHIT1 (Human) ELISA Kit is used for the quantitative measurement of human chitotriosidase.
Suitable Sample
Biological Medium, Cell Conditioned Medium, Cell Lysate, Plasma, Serum
Sample Volume
100 uL
Label
HRP-conjugate
Detection Method
Colorimetric
Assay Type
Quantitative
Intra-Assay
2.27%
Inter-Assay
3.85%
Reactivity
Human
Regulation Status
For research use only (RUO)
Quality Control Testing
Standard Curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store in the dark at 4°C. Avoid prolonged exposure to light.
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Applications
Quantification
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Gene Info — CHIT1
Entrez GeneID
1118Gene Name
CHIT1
Gene Alias
CHI3, CHIT, FLJ00314, MGC125322
Gene Description
chitinase 1 (chitotriosidase)
Omim ID
600031Gene Ontology
HyperlinkGene Summary
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. [provided by RefSeq
Other Designations
chitotriosidase|plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
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Interactome
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Pathway
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Disease
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