LSD1 Demethylase Activity/Inhibition Assay Kit (Colorimetric)
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The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
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Specification
Product Description
LSD1 Demethylase Activity/Inhibition Assay Kit (Colorimetric) is use for screening LSD1 demethylase inhibitors.
Suitable Sample
Cultured Cells and Fresh Tissues
Detection Method
Colorimetric
Regulation Status
For research use only (RUO)
Quality Control Testing
Standard Curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store LD1, LD5, LD7, LD8 and 8-Well Assay Strips at 4°C away from light.
Store LD3, LD4, and LD6 at -20°C away from light.
Store remaining components (LD2, LD9, and Adhesive Covering Firm) at room temperature away from light. -
Applications
Functional Study
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Publication Reference
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LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer.
Boulding T, McCuaig RD, Tan A, Hardy K, Wu F, Dunn J, Kalimutho M, Sutton CR, Forwood JK, Bert AG, Goodall GJ, Malik L, Yip D, Dahlstrom JE, Zafar A, Khanna KK, Rao S.
Scientific Reports 2018 Jan; 8(1):73.
Application：Func, Human, MCF-7, MDA-MB-231 cells.
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LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer.
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