Phosphorylated NEFH (Human) ELISA Kit
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The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
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Specification
Product Description
Phosphorylated NEFH (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of phosphorylated NEFH.
Suitable Sample
Cerebrospinal Fluid, Plasma, Serum
Sample Volume
100 uL (diluted)
Label
HRP-conjugate
Detection Method
Colorimetric
Assay Type
Quantitative
Limit of Detection
24 pg/mL
Regulation Status
For research use only (RUO)
Quality Control Testing
Standard Curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store at 4°C on dry atmosphere away from light.
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Applications
Quantification
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Gene Info — NEFH
Entrez GeneID
4744Gene Name
NEFH
Gene Alias
NFH
Gene Description
neurofilament, heavy polypeptide
Gene Ontology
HyperlinkGene Summary
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq
Other Designations
neurofilament triplet H protein|neurofilament, heavy polypeptide 200kDa
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Interactome
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Pathway
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Disease
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Publication Reference
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Neurofilament levels, disease activity and brain volume during follow-up in multiple sclerosis.
Håkansson I, Tisell A, Cassel P, Blennow K, Zetterberg H, Lundberg P, Dahle C, Vrethem M, Ernerudh J.
Journal of Neuroinflammation 2018 Jul; 15(1):209.
Application：ELISA, Human, CSF.
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Neurofilament light chain in cerebrospinal fluid and prediction of disease activity in clinically isolated syndrome and relapsing-remitting multiple sclerosis.
Håkansson I, Tisell A, Cassel P, Blennow K, Zetterberg H, Lundberg P, Dahle C, Vrethem M, Ernerudh J.
European Journal of Neurology 2017 May; 24(5):703.
Application：Quant, Human , Cerebrospinal fluid from patients with clinically isolated syndrome (CIS).
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Neurofilament levels, disease activity and brain volume during follow-up in multiple sclerosis.
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