NF-kB (p65) Transcription Factor Assay Kit
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Result data
Result data
(A) Typical data generated using Transcription Factor NF-kappaB (human p65) Positive Control. (B) Typical data in absorbance of positive control by dsDNA competitor.
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Specifications
Product Description
NF-kB (p65) Transcription Factor Assay Kit is a non-radioactive method for detecting specific transcription factor DNA binding activity.
Regulation Status
For research use only (RUO)
Storage Instruction
Store the kit at -80°C temporarily. For best results, store the components as described in the protocol.
Note
Result data
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Applications
Functional Study
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Publication Reference
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Identification and Characterization of a Novel Indoleamine 2,3-Dioxygenase 1 Protein Degrader for Glioblastoma.
Lakshmi R Bollu, Prashant V Bommi, Paige J Monsen, Lijie Zhai, Kristen L Lauing, April Bell, Miri Kim, Erik Ladomersky, Xinyu Yang, Leonidas C Platanias, Daniela E Matei, Marcelo G Bonini, Hidayatullah G Munshi, Rintaro Hashizume, Jennifer D Wu, Bin Zhang, Charles David James, Peiwen Chen, Masha Kocherginsky, Craig Horbinski, Michael D Cameron, Arabela A Grigorescu, Bakhtiar Yamini, Rimas V Lukas, Gary E Schiltz, Derek A Wainwright.
Journal of Medicinal Chemistry 2022 Dec; 65(23):15642.
Application：Func, Human, U87 MG cells.
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Lin28b is involved in curcumin-reversed paclitaxel chemoresistance and associated with poor prognosis in hepatocellular carcinoma.
Tian N, Shangguan W, Zhou Z, Yao Y, Fan C, Cai L.
Journal of Cancer 2019 Oct; 10(24):6074.
Application：Func, Human, Hep3B cells.
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Protective effect of Cordyceps sinensis extract on lipopolysaccharide induced acute lung injury in mice.
Fu S, Lu W, Yu W, Hu J.
Bioscience Reports 2019 Jun; 39(6):BSR2019078.
Application：Func, Mouse, Mouse lungs.
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Inactivation of the tyrosine phosphatase SHP-2 drives vascular dysfunction in Sepsis.
Heun Y, Pircher J, Czermak T, Bluem P, Hupel G, Bohmer M, Kraemer BF, Pogoda K, Pfeifer A, Woernle M, Ribeiro A, Hübner M, Kreth S, Claus RA, Weis S, Ungelenk L, Krötz F, Pohl U, Mannell H.
EBioMedicine 2019 Apr; 42:120.
Application：Func, Human, HUVECs.
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Indoor nanoscale particulate matter-induced coagulation abnormality based on a human 3D microvascular model on a microfluidic chip.
Li Y, Hu C, Wang P, Liu Y, Wang L, Pi Q, Gong Z, Yang X, Mak M, Wu Y.
Journal of Nanobiotechnology 2019 Feb; 17(1):20.
Application：Func, Human, Supernatants collected from HUVECs culture medium.
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Paclitaxel-sensitization enhanced by curcumin involves down-regulation of nuclear factor-iB and Lin28 in Hep3B cells.
Zhou M, Li Z, Han Z, Tian N.
Journal of Receptor and Signal Transduction Research 2015 Jun; 35(6):618.
Application：Func, Human, Nuclear extracts from Hep3B cells.
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Identification and Characterization of a Novel Indoleamine 2,3-Dioxygenase 1 Protein Degrader for Glioblastoma.
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