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PLAT (Human) Chromogenic Activity Assay Kit

  • Catalog # : KA0974
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  • Specification
  • Product Description:
  • PLAT (Human) Chromogenic Activity Assay Kit is developed to determine human PLAT activity in cell culture supernatants.
  • Calibration Range:
  • 0.039 to 40.00 IU/mL
  • Limit of Detection:
  • 0.03 IU/mL
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Standard curve

    QC Testing of KA0974
    The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
  • Storage Instruction:
  • Store components of the kit at 4°C or -20°C as described in the protocol.
  • Suitable Sample:
  • Cell Culture Supernatant, Plasma
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Functional Study
  • Application Image
  • Functional Study
  • Gene Information
  • Entrez GeneID:
  • 5327
  • Gene Name:
  • PLAT
  • Gene Alias:
  • DKFZp686I03148,T-PA,TPA
  • Gene Description:
  • plasminogen activator, tissue
  • Gene Summary:
  • This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • alteplase,plasminogen activator, tissue type,reteplase,t-plasminogen activator,tissue plasminogen activator (t-PA)
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