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Last updated: 2017/7/16
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Caspase-12 Staining Kit (Green)

  • Catalog # : KA0734
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  • Specification
  • Product Description:
  • Caspase-12 Staining Kit (Green) is used for sensitive detection of activated caspase-2 in living cells with fluorescein.
  • Reactivity:
  • Mammals
  • Storage Instruction:
  • Store the kit at -20°C.
  • Suitable Sample:
  • Cell
  • Detection Method:
  • Fluorometric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Functional Study
  • Flow Cytometry
  • Application Image
  • Functional Study
  • Flow Cytometry
  • Gene Information
  • Gene Name:
  • CASP12
  • Gene Alias:
  • CASP12P1
  • Gene Description:
  • caspase 12 (gene/pseudogene)
  • Gene Summary:
  • Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene, CASP12, is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. [provided by RefSeq
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