MICA (Human) ELISA Kit
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Specifications
Product Description
MICA (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human MICA.
Suitable Sample
Cell Culture Supernatant, Plasma, Serum, Tissue Lysate
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
62.5 to 4000 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
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Applications
Quantification
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Gene Info — MICA
Entrez GeneID
4276Gene Name
MICA
Gene Alias
FLJ60820, MGC111087, PERB11.1
Gene Description
MHC class I polypeptide-related sequence A
Omim ID
600169Gene Ontology
HyperlinkGene Summary
MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. [provided by RefSeq
Other Designations
HLA class I antigen|MHC class I chain-related gene A protein|MHC class I chain-related protein A|OTTHUMP00000029088|OTTHUMP00000035033|OTTHUMP00000035034|Stress inducible class I homolog
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Pathways
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Diseases
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Publication Reference
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Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells.
Groh V, Steinle A, Bauer S, Spies T.
The Journal of Cell Biology 1998 Aug; 142(3):803.
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Genes in a 220-kb region spanning the TNF cluster in human MHC.
Nalabolu SR, Shukla H, Nallur G, Parimoo S, Weissman SM.
Genomics 1996 Jan; 31(2):215.
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A second lineage of mammalian major histocompatibility complex class I genes.
Bahram S, Bresnahan M, Geraghty DE, Spies T.
PNAS 1994 Jul; 91(14):6259.
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Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells.
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