IL7 (Human) ELISA Kit
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Specification
Product Description
IL7 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human IL7.
Suitable Sample
Cell Culture Supernatant, Plasma, Serum, Biological Fluids
Sample Volume
100 uL
Label
HRP-conjugate
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
1.5 to 500 pg/mL
Limit of Detection
1 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store the kit at 4°C.
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Applications
Quantification
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Gene Info — IL7
Entrez GeneID
3574Gene Name
IL7
Gene Alias
IL-7
Gene Description
interleukin 7
Omim ID
146660Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. [provided by RefSeq
Other Designations
IL7 nirs variant 6
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Interactome
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Pathway
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Disease
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Publication Reference
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Interleukin 7 is produced by human intestinal epithelial cells and regulates the proliferation of intestinal mucosal lymphocytes.
Watanabe M, Ueno Y, Yajima T, Iwao Y, Tsuchiya M, Ishikawa H, Aiso S, Hibi T, Ishii H.
The Journal of Clinical Investigation 1995 Jun; 95(6):2945.
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Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.
von Freeden-Jeffry U, Vieira P, Lucian LA, McNeil T, Burdach SE, Murray R.
The Journal of Experimental Medicine 1995 Apr; 181(4):1519.
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Interleukin-7 expression during mouse thymus development.
Wiles MV, Ruiz P, Imhof BA.
European Journal of Immunology 1992 Apr; 22(4):1037.
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Interleukin 7 is produced by human intestinal epithelial cells and regulates the proliferation of intestinal mucosal lymphocytes.
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