IL6R (Human) ELISA Kit
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Specification
Product Description
IL6R (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human IL6R.
Suitable Sample
Cell Culture Supernatant, Plasma, Serum
Sample Volume
100 uL
Label
HRP-conjugate
Detection Method
Colorimetric
Assay Type
Quantitative
Intra-Assay
6.61%
Inter-Assay
6.68%
Spiking Recovery
Serum: 101.00%, Plasma: 100.00%, Cell Culture Supernatant: 99.00%
Calibration Range
31.2 to 2000 pg/mL
Limit of Detection
31.2 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store the kit at 4°C.
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Applications
Quantification
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Gene Info — IL6R
Entrez GeneID
3570Gene Name
IL6R
Gene Alias
CD126, IL-6R-1, IL-6R-alpha, IL6RA, MGC104991
Gene Description
interleukin 6 receptor
Omim ID
147880Gene Ontology
HyperlinkGene Summary
Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
CD126 antigen|OTTHUMP00000034320|interleukin 6 receptor alpha subunit
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Interactome
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Publication Reference
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Human soluble IL-6 receptor: its detection and enhanced release by HIV infection.
Honda M, Yamamoto S, Cheng M, Yasukawa K, Suzuki H, Saito T, Osugi Y, Tokunaga T, Kishimoto T.
Journal of Immunology 1992 Apr; 148(7):2175.
Application:Quant, Human, Recombinant proteins, Serum, U-937 cells.
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Preparation of soluble murine IL-6 receptor and anti-murine IL-6 receptor antibodies.
Saito T, Yasukawa K, Suzuki H, Futatsugi K, Fukunaga T, Yokomizo C, Koishihara Y, Fukui H, Ohsugi Y, Yawata H, et al..
Journal of Immunology 1991 Jul; 147(1):168.
Application:Quant, Human, Recombinant proteins.
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Purification and characterization of soluble human IL-6 receptor expressed in CHO cells.
Yasukawa K, Saito T, Fukunaga T, Sekimori Y, Koishihara Y, Fukui H, Ohsugi Y, Matsuda T, Yawata H, Hirano T, et al..
Journal of Biochemistry 1990 Oct; 108(4):673.
Application:Quant, Recombinant proteins.
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Human soluble IL-6 receptor: its detection and enhanced release by HIV infection.
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