CCL7 (Human) ELISA Kit
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Specification
Product Description
CCL7 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human CCL7.
Suitable Sample
Cell Culture Supernatant, Plasma, Serum
Sample Volume
100 uL
Label
HRP-conjugate
Detection Method
Colorimetric
Assay Type
Quantitative
Intra-Assay
5.56%
Inter-Assay
6.64%
Spiking Recovery
Serum: 102.00%, Plasma: 101.40%, Cell Culture Supernatant: 102.10%
Calibration Range
30 to 1540 pg/mL
Limit of Detection
30 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store the kit at 4°C.
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Applications
Quantification
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Gene Info — CCL7
Entrez GeneID
6354Gene Name
CCL7
Gene Alias
FIC, MARC, MCP-3, MCP3, MGC138463, MGC138465, NC28, SCYA6, SCYA7
Gene Description
chemokine (C-C motif) ligand 7
Omim ID
158106Gene Ontology
HyperlinkGene Summary
This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq
Other Designations
monocyte chemoattractant protein 3|monocyte chemotactic protein 3|small inducible cytokine A7 (monocyte chemotactic protein 3)
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Interactome
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Pathway
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Disease
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Publication Reference
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Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors. C-C CKR1, a receptor for macrophage inflammatory protein-1 alpha/Rantes, is also a functional receptor for MCP3.
Ben-Baruch A, Xu L, Young PR, Bengali K, Oppenheim JJ, Wang JM.
The Journal of Biological Chemistry 1995 Sep; 270(38):22123.
Application:Quant, Human, Human leukocytes.
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The human MCP-3 gene (SCYA7): cloning, sequence analysis, and assignment to the C-C chemokine gene cluster on chromosome 17q11.2-q12.
Opdenakker G, Fiten P, Nys G, Froyen G, Van Roy N, Speleman F, Laureys G, Van Damme J.
Genomics 1994 May; 21(2):403.
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Monocyte chemotactic protein 3 is a most effective basophil- and eosinophil-activating chemokine.
Dahinden CA, Geiser T, Brunner T, von Tscharner V, Caput D, Ferrara P, Minty A, Baggiolini M.
The Journal of Experimental Medicine 1994 Feb; 179(2):751.
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Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors. C-C CKR1, a receptor for macrophage inflammatory protein-1 alpha/Rantes, is also a functional receptor for MCP3.
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