APOC2 (Human) ELISA Kit
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Specifications
Product Description
APOC2 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human APOC2.
Suitable Sample
Cell Culture Sample, Plasma and Serum
Sample Volume
50 uL
Label
Peroxidase-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
0.016 to 4 ug/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store components of the kit at 4°C or -20°C as described in the protocol.
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Applications
Quantification
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Gene Info — APOC2
Entrez GeneID
344Gene Name
APOC2
Gene Alias
MGC75082
Gene Description
apolipoprotein C-II
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. [provided by RefSeq
Other Designations
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Interactomes
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Diseases
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Publication Reference
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Fibrillar amyloid protein present in atheroma activates CD36 signal transduction.
Medeiros LA, Khan T, El Khoury JB, Pham CL, Hatters DM, Howlett GJ, Lopez R, O'Brien KD, Moore KJ.
Journal of Biological Chemistry 2004 Mar; 279(11):10643.
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Human apolipoprotein C-II forms twisted amyloid ribbons and closed loops.
Hatters DM, MacPhee CE, Lawrence LJ, Sawyer WH, Howlett GJ.
Biochemistry 2000 Jul; 39(28):8276.
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Hypertriglyceridaemia due to genetic defects in lipoprotein lipase and apolipoprotein C-II.
Fojo SS, Brewer HB.
Journal of Internal Medicine 1992 Jun; 231(6):669.
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Fibrillar amyloid protein present in atheroma activates CD36 signal transduction.
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