APOA1 (Human) ELISA Kit
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Specification
Product Description
APOA1 (Human) ELISA Kit is a competitive enzyme immunoassay for the quantitative measurement of human APOA1 in plasma, serum.
Suitable Sample
Plasma, Serum
Sample Volume
25 uL
Label
Peroxidase-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
1.25 to 40 ug/mL
Limit of Detection
0.13 ug/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store components of the kit at 4°C or -20°C as described in the protocol.
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Applications
Quantification
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Gene Info — APOA1
Entrez GeneID
335Gene Name
APOA1
Gene Alias
MGC117399
Gene Description
apolipoprotein A-I
Gene Ontology
HyperlinkGene Summary
This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. [provided by RefSeq
Other Designations
OTTHUMP00000069346|OTTHUMP00000069347|OTTHUMP00000069348|apolipoprotein A1
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Interactome
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Pathway
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Disease
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Publication Reference
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ApoA1, ApoJ and ApoE Plasma Levels and Genotype Frequencies in Cerebral Amyloid Angiopathy.
Montañola A, de Retana SF, López-Rueda A, Merino-Zamorano C, Penalba A, Fernández-Álvarez P, Rodríguez-Luna D, Malagelada A, Pujadas F, Montaner J, Hernández-Guillamon M.
Neuromolecular Medicine 2016 Mar; 18(1):99.
Application:ELISA, Human, Plasma.
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Increased level of MSU crystal-bound protein apolipoprotein A-I in acute gouty arthritis.
Chiang SL, Ou TT, Wu YJ, Tu HP, Lu CY, Huang CM, Kuo TM, Wang TN, Chou CH, Ko YC.
Scandinavian Journal of Rheumatology 2014 Sep; 43(6):498.
Application:ELISA, Human, WRL-68 cells.
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Comprehensive plasma profiling for the characterization of graft-versus-host disease biomarkers.
De Bock M, Beguin Y, Leprince P, Willems E, Baron F, Deroyer C, Seidel L, Cavalier E, de Seny D, Malaise M, Gothot A, Merville MP, Fillet M.
Talanta 2014 Jul; 125:265.
Application:ELISA, Human, Serum.
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The structure of apolipoprotein A-I in high density lipoproteins.
Davidson WS, Thompson TB.
The Journal of Biological Chemistry 2007 Aug; 282(31):22249.
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Pathways for oxidation of high-density lipoprotein in human cardiovascular disease.
Shao B, Oda MN, Vaisar T, Oram JF, Heinecke JW.
Curr Opin Mol Ther 2006 Jun; 8(3):198.
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Electron microscopic study on reassembly of plasma high density apoprotein with various lipids.
Forte TM, Nichols AV, Gong EL, Levy RI, Lux S.
Biochimica et Biophysica Acta 1971 Nov; 248(2):381.
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ApoA1, ApoJ and ApoE Plasma Levels and Genotype Frequencies in Cerebral Amyloid Angiopathy.
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