SERPINA1 (Human) ELISA Kit
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Specifications
Product Description
SERPINA1 (Human) ELISA Kit is a competitive enzyme immunoassay for the quantitative measurement of human SERPINA1 in plasma and serum.
Suitable Sample
Plasma, Serum
Sample Volume
25 uL
Label
Peroxidase-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
0.039 to 40 ug/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store components of the kit at 4°C or -20°C as described in the protocol.
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Applications
Quantification
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Gene Info — SERPINA1
Entrez GeneID
5265Gene Name
SERPINA1
Gene Alias
A1A, A1AT, AAT, MGC23330, MGC9222, PI, PI1, PRO2275
Gene Description
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin|serine (or cysteine) proteinase inhibitor, clade A, member 1|serine proteinase inhibitor, clade A, member 1
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Case study on human α1‐antitrypsin: Recombinant protein titers obtained by commercial ELISA kits are inaccurate.
Hansen HG, Kildegaard HF, Lee GM, Kol S.
Biotechnology Journal 2016 Nov; 11(12):1648.
Application:Quan, Human, CHO-S suspension cells.
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Quantitative proteomic analysis exploring progression of colorectal cancer: Modulation of the serpin family.
Peltier J, Roperch JP, Audebert S, Borg JP, Camoin L.
Journal of Proteomics 2016 Oct; 148:139.
Application:ELISA, Human, Serum.
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Results of a survey of patients with alpha-1 antitrypsin deficiency.
Strange C, Stoller JK, Sandhaus RA, Dickson R, Turino G.
Respiration 2006 Aug; 73(2):185.
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Emphysema in alpha1-antitrypsin deficiency: does replacement therapy affect outcome?
Abboud RT, Ford GT, Chapman KR.
Treatments in Respiratory Medicine 2005 Feb; 4(1):1.
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Haplotypes of the alpha-1 antitrypsin gene in healthy controls and Z deficiency patients.
Chappell S, Guetta-Baranes T, Batowski K, Yiannakis E, Morgan K, O'Connor C, MacNee W, Kalsheker N.
Human Mutation 2004 Dec; 24(6):535.
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Case study on human α1‐antitrypsin: Recombinant protein titers obtained by commercial ELISA kits are inaccurate.
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