LTA (Human) ELISA Kit
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Specification
Product Description
LTA (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human LTA.
Suitable Sample
Cell Culture Supernatant, Plasma (Citrate, EDTA, Heparin) and Serum
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
62.5 to 4000 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
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Applications
Quantification
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Gene Info — LTA
Entrez GeneID
4049Gene Name
LTA
Gene Alias
LT, TNFB, TNFSF1
Gene Description
lymphotoxin alpha (TNF superfamily, member 1)
Omim ID
153440Gene Ontology
HyperlinkGene Summary
The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis
Other Designations
OTTHUMP00000029184|OTTHUMP00000037612|OTTHUMP00000037613|OTTHUMP00000165897|lymphotoxin alpha|tumor necrosis factor beta
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Publication Reference
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An association study in essential hypertension using functional polymorphisms in lymphotoxin-alpha gene.
Nakayama T, Soma M, Sato N, Haketa A, Kosuge K, Aoi N, Sato M, Izumi Y, Matsumoto K, Kanmatsuse K, Kokubun S.
American Journal of Hypertension 2004 Nov; 17(11 Pt 1):1045.
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Allele-specific repression of lymphotoxin-alpha by activated B cell factor-1.
Knight JC, Keating BJ, Kwiatkowski DP.
Nature Genetics 2004 Apr; 36(4):394.
Application:Quant, Human, Human lymphoblastoid cell lines.
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An association study in essential hypertension using functional polymorphisms in lymphotoxin-alpha gene.
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