CCL5 (Human) ELISA Kit
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Specification
Product Description
CCL5 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human CCL5.
Suitable Sample
Cell Culture Supernates, Plasma (heparin, EDTA, citrate), Serum and Urine
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
15.6 to 1000 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
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Applications
Quantification
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Gene Info — CCL5
Entrez GeneID
6352Gene Name
CCL5
Gene Alias
D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228
Gene Description
chemokine (C-C motif) ligand 5
Omim ID
187011Gene Ontology
HyperlinkGene Summary
This gene is one of several CC cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor CCR5 and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. [provided by RefSeq
Other Designations
SIS-delta|T-cell specific RANTES protein|T-cell specific protein p288|beta-chemokine RANTES|regulated upon activation, normally T-expressed, and presumably secreted|small inducible cytokine A5|small inducible cytokine A5 (RANTES)|small inducible cytokine
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Interactome
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Pathway
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Disease
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Publication Reference
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Polymorphism in RANTES chemokine promoter affects HIV-1 disease progression.
Liu H, Chao D, Nakayama EE, Taguchi H, Goto M, Xin X, Takamatsu JK, Saito H, Ishikawa Y, Akaza T, Juji T, Takebe Y, Ohishi T, Fukutake K, Maruyama Y, Yashiki S, Sonoda S, Nakamura T, Nagai Y, Iwamoto A, Shioda T.
PNAS 1999 Apr; 96(8):4581.
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A human T cell-specific molecule is a member of a new gene family.
Schall TJ, Jongstra J, Dyer BJ, Jorgensen J, Clayberger C, Davis MM, Krensky AM.
Journal of Immunology 1988 Aug; 141(3):1018.
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Polymorphism in RANTES chemokine promoter affects HIV-1 disease progression.
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