NTF3 (Human) ELISA Kit
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Specification
Product Description
NTF3 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human NTF3.
Suitable Sample
Cell Culture Supernatant, Serum
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
15.6 to 1000 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
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Applications
Quantification
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Gene Info — NTF3
Entrez GeneID
4908Gene Name
NTF3
Gene Alias
HDNF, MGC129711, NGF-2, NGF2, NT3
Gene Description
neurotrophin 3
Omim ID
162660Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq
Other Designations
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Publication Reference
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Identification of an essential nonneuronal function of neurotrophin 3 in mammalian cardiac development.
Donovan MJ, Hahn R, Tessarollo L, Hempstead BL.
Nature Genetics 1996 Oct; 14(2):210.
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Targeted mutation in the neurotrophin-3 gene results in loss of muscle sensory neurons.
Tessarollo L, Vogel KS, Palko ME, Reid SW, Parada LF.
PNAS 1994 Dec; 91(25):11844.
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Chromosomal mapping of brain-derived neurotrophic factor and neurotrophin-3 genes in man and mouse.
Ozcelik T, Rosenthal A, Francke U.
Genomics 1991 Jul; 10(3):569.
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Identification of an essential nonneuronal function of neurotrophin 3 in mammalian cardiac development.
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