CCL3 (Human) ELISA Kit
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Specification
Product Description
CCL3 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human CCL3.
Suitable Sample
Cell Culture Supernatant, Plasma (citrate, EDTA, heparin), Serum
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
15.6 to 1000 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
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Applications
Quantification
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Gene Info — CCL3
Entrez GeneID
6348Gene Name
CCL3
Gene Alias
G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3
Gene Description
chemokine (C-C motif) ligand 3
Gene Ontology
HyperlinkGene Summary
Macrophage inflammatory protein-1 is a so-called monokine that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes (Wolpe et al., 1988 [PubMed 3279154]). Sherry et al. (1988) [PubMed 3058856] demonstrated 2 protein components of MIP1, called by them alpha and beta.[supplied by OMIM
Other Designations
LD78 alpha beta|small inducible cytokine A3 (homologous to mouse Mip-1a)
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Interactome
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Pathway
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Disease
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Publication Reference
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Requirement of MIP-1 alpha for an inflammatory response to viral infection.
Cook DN, Beck MA, Coffman TM, Kirby SL, Sheridan JF, Pragnell IB, Smithies O.
Science 1995 Sep; 269(5230):1583.
Application:WB-Ce, Mouse, Mouse macrophages.
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Structures of human genes coding for cytokine LD78 and their expression.
Nakao M, Nomiyama H, Shimada K.
Molecular and Cellular Biology 1990 Jul; 10(7):3646.
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Macrophage inflammatory proteins 1 and 2: members of a novel superfamily of cytokines.
Wolpe SD, Cerami A.
FASEB Journal 1989 Dec; 3(14):2565.
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Requirement of MIP-1 alpha for an inflammatory response to viral infection.
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