Protein Phosphatase Cdc25A Fluorometric (Human) Assay Kit
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More Files
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Dose dependent curve of recombinant Cdc25A catalytic domain.
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Specification
Product Description
Protein Phosphatase Cdc25A Fluorometric (Human) Assay Kit is a fluorometric and non-radioactive assay designed to measure the activity of Cdc25A protein phosphatase.
Reactivity
Human
Regulation Status
For research use only (RUO)
Quality Control Testing
Dose dependent curve
Dose dependent curve of recombinant Cdc25A catalytic domain.
Storage Instruction
Store the kit at -20°C. Recombinant protein should be stored at -80°C.
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Applications
Functional Study
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Gene Info — CDC25A
Entrez GeneID
993Gene Name
CDC25A
Gene Alias
CDC25A2
Gene Description
cell division cycle 25 homolog A (S. pombe)
Omim ID
116947Gene Ontology
HyperlinkGene Summary
CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
M-phase inducer phosphatase 1|cell division cycle 25A|dual specificity phosphatase CDC25A
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Interactome
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Pathway
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Disease
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