COMP (Human) ELISA Kit
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specifications
Product Description
COMP (Human) ELISA Kit is a double monoclonal sandwich enzyme immunoassay for the quantitative measurement of human COMP in serum or plasma.
Suitable Sample
Plasma (Citrate, EDTA, Heparin), Serum
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
4 to 128 ng/mL
Limit of Detection
0.4 ng/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store the kit at 4°C.
-
Applications
Quantification
-
Gene Info — COMP
Entrez GeneID
1311Gene Name
COMP
Gene Alias
EDM1, EPD1, MED, MGC131819, MGC149768, PSACH, THBS5
Gene Description
cartilage oligomeric matrix protein
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq
Other Designations
cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple)|cartilage oligomeric matrix protein(pseudoachondroplasia, epiphyseal dysplasia 1, multiple)|pseudoachondroplasia (epiphyseal dysplasia 1, multiple)|thrombospondin
-
Interactomes
-
Pathways
-
Diseases
-
Publication Reference
-
An exploratory study to investigate the association between age, physical activity, femoral trochlear cartilage thickness and biomarkers of tissue metabolism in adult males.
Harry M Roberts, Claire L Griffith-McGeever, Julian A Owen, Lewis Angell, Jonathan P Moore, Jeanette M Thom.
European Journal of Applied Physiology 2021 Jul; 121(7):1871.
Application:Quant, Human, Human serum.
-
The effect of aerobic walking and lower body resistance exercise on serum COMP and hyaluronan, in both males and females.
Roberts HM, Moore JP, Thom JM.
European Journal of Applied Physiology 2018 Jun; 118(6):1095.
Application:ELISA, Human, Serum.
-
Cartilage turnover and intra-articular corticosteroid injections in knee osteoarthritis.
Klocke R, Levasseur K, Kitas GD, Smith JP, Hirsch G.
Rheumatology International 2018 Feb; 38:455.
Application:ELISA, Human, urinary, serum biomarkers.
-
Cartilage oligomeric protein, matrix metalloproteinase-3, and Coll2-1 as serum biomarkers in knee osteoarthritis: a cross-sectional study.
Georgiev T, Ivanova M, Kopchev A, Velikova T, Miloshov A, Kurteva E, Yuzeir K, Penkov M, Kabakchieva P, Rashkov R, Stoilov R.
Rheumatology International 2017 Nov; [Epub].
Application:Quant, Human, Serum from patients with primary knee osteoarthritis.
-
The effect of vigorous running and cycling on serum COMP, lubricin, and femoral cartilage thickness: a pilot study.
Roberts HM, Moore JP, Griffith-McGeever CL, Fortes MB, Thom JM.
European Journal of Applied Physiology 2016 Jun; 116(8):1467.
Application:Quan, Human, Human serum.
-
An exploratory study to investigate the association between age, physical activity, femoral trochlear cartilage thickness and biomarkers of tissue metabolism in adult males.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com