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Last updated: 2017/12/10
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SPANXB1 purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00728695-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human SPANXB1 protein.
  • Immunogen:
  • SPANXB1 (NP_115850.1, 1 a.a. ~ 103 a.a) full-length human protein.
  • Sequence:
  • MGQQSSVRRLKRSVPCESNEANEANEANKTMPETPTGDSDPQPAPKKMKTSESSTILVVRYRRNVKRTSPEELVNDHARENRINPDQMEEEEFIEITTERPKK
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of SPANXB1 expression in transfected 293T cell line (H00728695-T01) by SPANXB1 MaxPab polyclonal antibody.

    Lane 1: SPANXB1 transfected lysate(11.33 KDa).
    Lane 2: Non-transfected lysate.
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  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
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  • Gene Information
  • Gene Name:
  • SPANXB1
  • Gene Alias:
  • B1,SPANX-B,SPANXB
  • Gene Description:
  • SPANX family, member B1
  • Gene Summary:
  • Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-tail orientation with SPANX family member B2, which appears to be a duplication of the B1 locus. The SPANXB genes are unique members of this gene family, since they contain an additional 18 nt in their coding region compared to the majority of family members. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000024171,nuclear-associated protein SPAN-Xb,sperm protein associated with the nucleus, X chromosome, family member B1
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