INS-IGF2 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of INS-IGF2 expression in transfected 293T cell line (H00723961-T01) by INS-IGF2 MaxPab polyclonal antibody.
Lane 1: INS-IGF2 transfected lysate(22 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human INS-IGF2 protein.
Immunogen
INS-IGF2 (AAI53084.1, 1 a.a. ~ 200 a.a) full-length human protein.
Sequence
MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQASALSLSSSTSTWPEGLDATARAPPALVVTANIGQAGGSSSRQFRQRALGTSDSPVLFIHCPGAAGTAQGLEYRGRRVTTELVWEEVDSSPQPQGSESLPAQPPAQPAPQPEPQQAREPSPEVSCCGLWPRRPQRSQN
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of INS-IGF2 expression in transfected 293T cell line (H00723961-T01) by INS-IGF2 MaxPab polyclonal antibody.
Lane 1: INS-IGF2 transfected lysate(22 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — INS-IGF2
Entrez GeneID
723961GeneBank Accession#
BC153083.1Protein Accession#
AAI53084.1Gene Name
INS-IGF2
Gene Alias
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Gene Description
INS-IGF2 readthrough transcript
Gene Ontology
HyperlinkGene Summary
This locus includes two alternatively spliced read-through transcript variants which align to the INS gene in the 5' region and to the IGF2 gene in the 3' region. One transcript is predicted to encode a protein which shares the N-terminus with the INS protein but has a distinct and longer C-terminus, whereas the other transcript is a candidate for nonsense-mediated decay (NMD). The transcripts are imprinted and are paternally expressed in the limb and eye. [provided by RefSeq
Other Designations
insulin- insulin-like growth factor 2
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Disease
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Publication Reference
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Analysis artefacts of the INS-IGF2 fusion transcript.
Wernersson R, Frogne T, Rescan C, Hansson L, Bruun C, Gronborg M, Jensen JN, Madsen OD.
BMC Molecular Biology 2015 Jul; 16(1):13.
Application：IHC-P, Human, Pancreas.
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Autoimmunity against INS-IGF2 Protein Expressed in Human Pancreatic Islets.
Kanatsuna N, Taneera J, Vaziri-Sani F, Wierup N, Larsson HE, Delli A, Skarstrand H, Balhuizen A, Bennet H, Steiner DF, Torn C, Fex M, Lernmark A.
The Journal of Biological Chemistry 2013 Oct; 288(40):29013.
Application：IF, Human, Pancreas.
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Analysis artefacts of the INS-IGF2 fusion transcript.
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