MAP1LC3C (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human MAP1LC3C full-length ORF ( NP_001004343.1, 1 a.a. - 147 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLVPQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYASQETFGCLESAAPRDGSSLEDRPCNPL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
43.3
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MAP1LC3C
Entrez GeneID
440738GeneBank Accession#
NM_001004343.1Protein Accession#
NP_001004343.1Gene Name
MAP1LC3C
Gene Alias
LC3C
Gene Description
microtubule-associated protein 1 light chain 3 gamma
Gene Ontology
HyperlinkGene Summary
Autophagy is a highly regulated bulk degradation process that plays an important role in cellular maintenance and development. MAP1LC3C is 1 of 3 orthologs of the yeast autophagosome protein Atg8 (He et al., 2003 [PubMed 12740394]).[supplied by OMIM
Other Designations
LC3-like protein 2|MAP1 light chain 3-like protein 2|OTTHUMP00000037810
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Interactome
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Publication Reference
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Co-chaperone BAG3 enters autophagic pathway via its interaction with microtubule associated protein 1 light chain 3 beta.
Hagen Körschgen, Marius Baeken, Daniel Schmitt, Heike Nagel, Christian Behl.
Traffic (Copenhagen, Denmark) 2023 Sep; [Epub].
Application：Array, N/A, Oligopeptides.
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Diurnal Rhythms Spatially and Temporally Organize Autophagy.
Ryzhikov M, Ehlers A, Steinberg D, Xie W, Oberlander E, Brown S, Gilmore PE, Townsend RR, Lane WS, Dolinay T, Nakahira K, Choi AMK, Haspel JA.
Cell Reports 2019 Feb; 26(7):1880.
Application：WB, Mouse, Mouse livers.
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Co-chaperone BAG3 enters autophagic pathway via its interaction with microtubule associated protein 1 light chain 3 beta.
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