GTF2H5 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human GTF2H5 full-length ORF ( NP_997001.1, 1 a.a. - 71 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MVNVLKGVLIECDPAMKQFLLYLDESNALGKKFIIQDIDDTHVFVIAELVNVLQERVGELMDQNAFSLTQK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
34.5
Interspecies Antigen Sequence
Mouse (99); Rat (100)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GTF2H5
Entrez GeneID
404672GeneBank Accession#
NM_207118.1Protein Accession#
NP_997001.1Gene Name
GTF2H5
Gene Alias
C6orf175, TFB5, TGF2H5, TTD, TTD-A, TTDA, bA120J8.2
Gene Description
general transcription factor IIH, polypeptide 5
Gene Ontology
HyperlinkGene Summary
This gene encodes a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A. [provided by RefSeq
Other Designations
DNA repair syndrome trichothiodystrophy group A|OTTHUMP00000017501|TFIIH basal transcription factor complex TTDA subunit|trichothiodystrophy
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Interactome
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Pathway
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Disease
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