GTF2H5 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human GTF2H5 peptide using ARM Technology.
Immunogen
A synthetic peptide of human GTF2H5 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human GTF2H5 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — GTF2H5
Entrez GeneID
404672GeneBank Accession#
GTF2H5Gene Name
GTF2H5
Gene Alias
C6orf175, TFB5, TGF2H5, TTD, TTD-A, TTDA, bA120J8.2
Gene Description
general transcription factor IIH, polypeptide 5
Gene Ontology
HyperlinkGene Summary
This gene encodes a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A. [provided by RefSeq
Other Designations
DNA repair syndrome trichothiodystrophy group A|OTTHUMP00000017501|TFIIH basal transcription factor complex TTDA subunit|trichothiodystrophy
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