MAFA monoclonal antibody (M01), clone 2F1
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MAFA.
Immunogen
MAFA (NP_963883, 222 a.a. ~ 308 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEVGRLAKERDL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.31 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MAFA is 1 ng/ml as a capture antibody.ELISA
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Gene Info — MAFA
Entrez GeneID
389692GeneBank Accession#
NM_201589Protein Accession#
NP_963883Gene Name
MAFA
Gene Alias
RIPE3b1, hMafA
Gene Description
v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
Omim ID
610303Gene Ontology
HyperlinkGene Summary
MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS; MIM 176730) (Olbrot et al., 2002 [PubMed 12011435]).[supplied by OMIM
Other Designations
v-maf musculoaponeurotic fibrosarcoma oncogene homolog A
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Pathway
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