SUMO4 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SUMO4 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SUMO4 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SUMO4 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SUMO4
Entrez GeneID
387082GeneBank Accession#
SUMO4Gene Name
SUMO4
Gene Alias
IDDM5, SMT3H4, SUMO-4, dJ281H8.4
Gene Description
SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae)
Gene Ontology
HyperlinkGene Summary
This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism. [provided by RefSeq
Other Designations
OTTHUMP00000017390|SMT3 suppressor of mif two 3 homolog 2|SMT3 suppressor of mif two 3 homolog 4|small ubiquitin-like modifier 4 protein|small ubiquitin-like protein 4
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Disease
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