IL31 monoclonal antibody (M01), clone 5G9
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant IL31.
Immunogen
IL31 (NP_001014358.1, 24 a.a. ~ 164 a.a) full-length recombinant protein.
Sequence
SHTLPVRLLRPSDDVQKIVEELQSLSKMLLKDVEEEKGVLVSQNYTLPCLSPDAQPPNNIHSPAIRAYLKTIRQLDNKSVIDEIIEHLDKLIFQDAPETNISVPTDTHECKRFILTISQQFSECMDLALKSLTSGAQQATT
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (15.8 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — IL31
Entrez GeneID
386653GeneBank Accession#
NM_001014336.1Protein Accession#
NP_001014358.1Gene Name
IL31
Gene Alias
IL-31
Gene Description
interleukin 31
Omim ID
609509Gene Ontology
HyperlinkGene Summary
IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM
Other Designations
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Interactome
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Disease
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