TBC1D10C rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human TBC1D10C peptide using ARM Technology.
Immunogen
A synthetic peptide of human TBC1D10C is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human TBC1D10C peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — TBC1D10C
Entrez GeneID
374403GeneBank Accession#
TBC1D10CGene Name
TBC1D10C
Gene Alias
CARABIN, FLJ00332, MGC46488
Gene Description
TBC1 domain family, member 10C
Omim ID
610831Gene Ontology
HyperlinkGene Summary
Carabin is an endogenous inhibitor of calcineurin (see MIM 114105) that also inhibits the Ras (see MIM 190020) signaling pathway through its intrinsic Ras GTPase-activating protein activity (Pan et al., 2007 [PubMed 17230191]).[supplied by OMIM
Other Designations
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Interactome
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Disease
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