NMNAT3 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human NMNAT3 partial ORF ( NP_835471, 116 a.a. - 215 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
IQEIVEKFGLVCVGRVGHDPKGYIAESPILRMHQHNIHLAKEPVQNEISATYIRRALGQGQSVKYLIPDAVITYIKDHGLYTKGSTWKGKSTQSTEGKTS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NMNAT3
Entrez GeneID
349565GeneBank Accession#
NM_178177Protein Accession#
NP_835471Gene Name
NMNAT3
Gene Alias
PNAT-3, PNAT3
Gene Description
nicotinamide nucleotide adenylyltransferase 3
Omim ID
608702Gene Ontology
HyperlinkGene Summary
The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003 [PubMed 12574164]).[supplied by OMIM
Other Designations
pyridine nucleotide adenylyltransferase 3
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Pathway
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