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IRGM (Human) Recombinant Protein (Q01)

  • Catalog # : H00345611-Q01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Human IRGM partial ORF ( XP_293893.3, 99 a.a. - 181 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • TTLENYLMEMQFNRYDFIMVASAQFSMNHVMLAKTAEDMGKKFYIVWTKLDMDLSTGALPEVQLLQIRENVLENLQKERVCEY
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 34.87
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00345611-Q01
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Gene Name:
  • IRGM
  • Gene Alias:
  • IFI1,IRGM1,LRG-47,LRG47,MGC149263,MGC149264
  • Gene Description:
  • immunity-related GTPase family, M
  • Gene Summary:
  • Members of the p47 immunity-related GTPase (IRG) family, including IRGM, play an important role in the murine immune system; however, in humans this resistance system is greatly reduced. There is evidence that human IRGM plays a role in autophagy and control of intracellular mycobacteria (Bekpen et al., 2005; Singh et al., 2006 [PubMed 16888103]).[supplied by OMIM
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