NSMCE2 (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human NSMCE2 full-length ORF ( NP_775956.1, 1 a.a. - 247 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MPGRSSSNSGSTGFISFSGVESALSSLKNFQACINSGMDTASSVALDLVESQTEVSSEYSMDKAMVEFATLDRQLNHYVKAVQSTINHVKEERPEKIPDLKLLVEKKFLALQSKNSDADFQNNEKFVQFKQQLKELKKQCGLQADREADGTEGVDEDIIVTQSQTNFTCPITKEEMKKPVKNKVCGHTYEEDAIVRMIESRQKRKKKAYCPQIGCSHTDIRKSDLIQDEALRRAIENHNKKRHRHSE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
54.3
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NSMCE2
Entrez GeneID
286053GeneBank Accession#
NM_173685.1Protein Accession#
NP_775956.1Gene Name
NSMCE2
Gene Alias
C8orf36, FLJ32440, MMS21, NSE2
Gene Description
non-SMC element 2, MMS21 homolog (S. cerevisiae)
Gene Ontology
HyperlinkGene Summary
O
Other Designations
methyl methanesulfonate sensitivity gene 21|non-SMC element 2, MMS21 homolog
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Interactome
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Disease
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Publication Reference
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A genome-wide RNAi screen identifies the SMC5/6 complex as a non-redundant regulator of a Topo2a-dependent G2 arrest.
Deiss K, Lockwood N, Howell M, Segeren HA, Saunders RE, Chakravarty P, Soliman TN, Martini S, Rocha N, Semple R, Zalmas LP, Parker PJ.
Nucleic Acids Research 2019 Apr; 47(6):2906.
Application:Func, Recombinant protein.
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A genome-wide RNAi screen identifies the SMC5/6 complex as a non-redundant regulator of a Topo2a-dependent G2 arrest.
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