PNPLA1 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PNPLA1 protein.
Immunogen
PNPLA1 (AAI03906.1, 1 a.a. ~ 446 a.a) full-length human protein.
Sequence
MVQMMRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENVVVSEFTSKEELIEALYCSCFVPVYCGLIPPTYRGVWAFLTLPPQRYIDGGFTGMQPCAFWTDAITISTFSGQQDICPRDCPAIFHDFRMFNCSFQFSLENIARMTHALFPPDLVILHDYYYRGYEDAVLYLRRLNAVYLNSSSKRVIFPRVEVYCQIELALGNECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSHRPSLGPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVMESPAEDSNWVNKVFKKNKQKTSGTRKGFPRHPGSKKPSSKVQ
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PNPLA1 MaxPab polyclonal antibody. Western Blot analysis of PNPLA1 expression in human placenta.Western Blot (Transfected lysate)
Western Blot analysis of PNPLA1 expression in transfected 293T cell line (H00285848-T01) by PNPLA1 MaxPab polyclonal antibody.
Lane 1: PNPLA1 transfected lysate(49.06 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PNPLA1
Entrez GeneID
285848GeneBank Accession#
BC103905.1Protein Accession#
AAI03906.1Gene Name
PNPLA1
Gene Alias
FLJ38755, MGC119319, MGC119320, MGC119321, dJ50J22.1
Gene Description
patatin-like phospholipase domain containing 1
Gene Ontology
HyperlinkGene Summary
Human patatin-like phospholipases, such as PNPLA1, have been implicated in regulation of adipocyte differentiation and have been induced by metabolic stimuli (Wilson et al., 2006 [PubMed 16799181]).[supplied by OMIM
Other Designations
OTTHUMP00000016289|OTTHUMP00000039681
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Disease
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Publication Reference
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PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans.
Grall A, Guaguere E, Planchais S, Grond S, Bourrat E, Hausser I, Hitte C, Le Gallo M, Derbois C, Kim GJ, Lagoutte L, Degorce-Rubiales F, Radner FP, Thomas A, Kury S, Bensignor E, Fontaine J, Pin D, Zimmermann R, Zechner R, Lathrop M, Galibert F, Andre C, Fischer J.
Nature Genetics 2012 Jan; 44(2):140.
Application:WB-Ce, Human, Keratinocyte.
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PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans.
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