COX18 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human COX18 peptide using ARM Technology.
Immunogen
A synthetic peptide of human COX18 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human COX18 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — COX18
Entrez GeneID
285521GeneBank Accession#
COX18Gene Name
COX18
Gene Alias
COX18HS, FLJ38991, MGC126733
Gene Description
COX18 cytochrome c oxidase assembly homolog (S. cerevisiae)
Omim ID
610428Gene Ontology
HyperlinkGene Summary
COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).[supplied by OMIM
Other Designations
Cox18Hs1 protein|Cox18Hs2 protein|Cox18Hs3 protein|mitochondrial COX18
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Disease
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