SUMF1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human SUMF1 partial ORF ( NP_877437.2, 89 a.a. - 188 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
SKMVPIPAGVFTMGTDDPQIKQDGEAPARRVTIDAFYMDAYEVSNTEFEKFVNSTGYLTEAEKFGDSFVFEGMLSEQVKTNIQQAVAAAPWWLPVKGANW
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SUMF1
Entrez GeneID
285362GeneBank Accession#
NM_182760Protein Accession#
NP_877437.2Gene Name
SUMF1
Gene Alias
AAPA3037, FGE, MGC131853, MGC150436
Gene Description
sulfatase modifying factor 1
Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
C-alpha-formylglycine-generating enzyme|OTTHUMP00000115300
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Interactome
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Disease
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