BLOC1S2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human BLOC1S2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human BLOC1S2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human BLOC1S2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — BLOC1S2
Entrez GeneID
282991GeneBank Accession#
BLOC1S2Gene Name
BLOC1S2
Gene Alias
BLOS2, FLJ30135, MGC10120, RP11-316M21.4
Gene Description
biogenesis of lysosomal organelles complex-1, subunit 2
Gene Ontology
HyperlinkGene Summary
BLOC1S2 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules (Starcevic and Dell'Angelica, 2004 [PubMed 15102850]).[supplied by OMIM
Other Designations
biogenesis of lysosome-related organelles complex-1, subunit 2|centrosomal 10 kDa protein|centrosome protein oncogene
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Interactome
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