IL28B DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human IL28B DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MTGDCMPVLVLMAAVLTVTGAVPVARLRGALPDARGCHIAQFKSLSPQELQAFKRAKDALEESLLLKDCKCRSRLFPRTWDLRQLQVRERPVALEAELALTLKVLEATADTDPALGDVLDQPLHTLHHILSQLRACIQPQPTAGPRTRGRLHHWLHRLQEAPKKESPGCLEASVTFNLFRLLTRDLNCVASGDLCV
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — IL28B
Entrez GeneID
282617GeneBank Accession#
HQ258095.1Protein Accession#
ADR82849.1Gene Name
IL28B
Gene Alias
IFNL3, IL-28B, IL28C
Gene Description
interleukin 28B (interferon, lambda 3)
Omim ID
607402Gene Ontology
HyperlinkGene Summary
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq
Other Designations
interferon, lambda 3|interferon, lambda 4|interleukin 28B|interleukin 28C
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Pathway
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Disease
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