ASPM rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ASPM peptide using ARM Technology.
Immunogen
A synthetic peptide of human ASPM is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ASPM peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ASPM
Entrez GeneID
259266GeneBank Accession#
ASPMGene Name
ASPM
Gene Alias
ASP, Calmbp1, DKFZp686N06184, FLJ10517, FLJ10549, FLJ43117, MCPH5
Gene Description
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
Gene Ontology
HyperlinkGene Summary
The ASPM gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts (Bond et al., 2002 [PubMed 12355089]). The mouse gene Aspm is expressed specifically in the primary sites of prenatal cerebral cortical neurogenesis.[supplied by OMIM
Other Designations
OTTHUMP00000034411|asp (abnormal spindle)-like, microcephaly associated|microcephaly, primary autosomal recessive 5
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