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ASPM rabbit monoclonal antibody

  • Catalog # : H00259266-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human ASPM peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human ASPM is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human ASPM peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • GeneBank Accession#:
  • ASPM
  • Gene Name:
  • ASPM
  • Gene Alias:
  • ASP,Calmbp1,DKFZp686N06184,FLJ10517,FLJ10549,FLJ43117,MCPH5
  • Gene Description:
  • asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
  • Gene Summary:
  • The ASPM gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts (Bond et al., 2002 [PubMed 12355089]). The mouse gene Aspm is expressed specifically in the primary sites of prenatal cerebral cortical neurogenesis.[supplied by OMIM
  • Other Designations:
  • OTTHUMP00000034411,asp (abnormal spindle)-like, microcephaly associated,microcephaly, primary autosomal recessive 5
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