TMIE (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human TMIE partial ORF ( NP_671729, 79 a.a. - 140 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
NCRVPRTRKEIEARYLQRKAAKMYTDKLETVPPLNELTEVPGEDKKKKKKKKDSVDTVAIKV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
32.56
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TMIE
Entrez GeneID
259236GeneBank Accession#
NM_147196Protein Accession#
NP_671729Gene Name
TMIE
Gene Alias
DFNB6
Gene Description
transmembrane inner ear
Gene Ontology
HyperlinkGene Summary
This gene encodes a transmembrane inner ear protein. Studies in mouse suggest that this gene is required for normal postnatal maturation of sensory hair cells in the cochlea, including correct development of stereocilia bundles. This gene is one of multiple genes responsible for recessive non-syndromic deafness (DFNB), also known as autosomal recessive nonsyndromic hearing loss (ARNSHL), the most common form of congenitally acquired inherited hearing impairment. [provided by RefSeq
Other Designations
transmembrane inner ear protein
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Interactome
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Disease
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