NALCN rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human NALCN peptide using ARM Technology.
Immunogen
A synthetic peptide of human NALCN is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human NALCN peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — NALCN
Entrez GeneID
259232GeneBank Accession#
NALCNGene Name
NALCN
Gene Alias
CanIon, FLJ23913, FLJ44659, FLJ44764, MGC74524, VGCNL1, bA430M15.1
Gene Description
sodium leak channel, non-selective
Omim ID
611549Gene Ontology
HyperlinkGene Summary
NALCN forms a voltage-independent, nonselective, noninactivating cation channel permeable to Na+, K+, and Ca(2+). It is responsible for the neuronal background sodium leak conductance (Lu et al., 2007 [PubMed 17448995]).[supplied by OMIM
Other Designations
OTTHUMP00000018654|OTTHUMP00000018655|OTTHUMP00000018656|OTTHUMP00000040730|four repeat voltage-gated ion channel|voltage gated channel like 1
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Disease
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