SGMS1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human SGMS1 full-length ORF ( AAH42899, 1 a.a. - 413 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MKEVVYWSPKKVADWLLENAMPEYCEPLEHFTGQDLINLTQEDFKKPPLCRVSSDNGQRLLDMIETLKMEHHLEAHKNGHANGHLNIGVDIPTPDGSFSIKIKPNGMPNGYRKEMIKIPMPELERSQYPMEWGKTFLAFLYALSCFVLTTVMISVVHERVPPKEVQPPLPDTFFDHFNRVQWAFSICEINGMILVGLWLIQWLLLKYKSIISRRFFCIVGTLYLYRCITMYVTTLPVPGMHFNCSPKLFGDWEAQLRRIMKLIAGGGLSITGSHNMCGDYLYSGHTVMLTLTYLFIKEYSPRRLWWYHWICWLLSVVGIFCILLAHDHYTVDVVVAYYITTRLFWWYHTMANQQVLKEASQMNLLARVWWYRPFQYFEKNVQGIVPRSYHWPFPWPVVHLSRQVKYSRLVNDT
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
71.17
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SGMS1
Entrez GeneID
259230GeneBank Accession#
BC042899Protein Accession#
AAH42899Gene Name
SGMS1
Gene Alias
MGC17342, MOB, MOB1, SMS1, TMEM23
Gene Description
sphingomyelin synthase 1
Omim ID
611573Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is predicted to be a five-pass transmembrane protein. This gene may be predominately expressed in brain. [provided by RefSeq
Other Designations
OTTHUMP00000035396|hmob33 protein|medulla oblongata-derived protein|phosphatidylcholine:ceramide cholinephosphotransferase 1|putative membrane protein|transmembrane protein 23
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Interactome
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Pathway
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Disease
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Publication Reference
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Caspase-mediated inhibition of sphingomyelin synthesis is involved in FasL-triggered cell death.
Lafont E, Milhas D, Carpentier S, Garcia V, Jin ZX, Umehara H, Okazaki T, Schulze-Osthoff K, Levade T, Benoist H, Segui B.
Cell Death and Differentiation 2010 Apr; 17(4):642.
Application:Func, Recombinant protein.
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Caspase-mediated inhibition of sphingomyelin synthesis is involved in FasL-triggered cell death.
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