POLR2J2 (Human) Recombinant Protein (P02)
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More Files
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Specification
Product Description
Human POLR2J2 full-length ORF ( NP_116581.3, 1 a.a. - 115 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MNAPPAFESFLLFEGEKITINKDTKVPKACLFTINKEDHTLGNIIKSQLLKDPQVLFAGYKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRTCLLPLRLLP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
39.5
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — POLR2J2
Entrez GeneID
246721GeneBank Accession#
NM_032959.3Protein Accession#
NP_116581.3Gene Name
POLR2J2
Gene Alias
HRPB11B, MGC105050, MGC54043, RPB11b1
Gene Description
polymerase (RNA) II (DNA directed) polypeptide J2
Omim ID
609881Gene Ontology
HyperlinkGene Summary
This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo. [provided by RefSeq
Other Designations
DNA directed RNA polymerase II polypeptide J-related
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Pathway
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