ATP6V1C2 MaxPab rabbit polyclonal antibody (D01)
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human ATP6V1C2 protein.
Immunogen
ATP6V1C2 (AAH12142.1, 1 a.a. ~ 381 a.a) full-length human protein.
Sequence
MSEFWLISAPGDKENLQALERMNTVTSKSNLSYNTKFAIPDFKVGTLDSLVGLSDELGKLDTFAESLIRRMAQSVVEVMEDSKGKVQEHLLANGVDLTSFVTHFEWDMAKYPVKQPLVSVVDTIAKQLAQIEMDLKSRTAAYDTLKTNLENLEKKSMGNLFTRTLSDIVSKEDFVLDSEYLVTLLVIVPKPNYSQWQKTYESLSDMVVPRSTKLITEDKEGGLFTVTLFRKVIEDFKTKAKENKFTVREFYYDEKEIEREREEMARLLSDKKQQYGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAVLLQPHKKSSTKRLREVLNSVFRHLDEVAATSILDASVEIPGLQLNNQDYFPYVYFHIDLSLLD
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (82); Rat (83)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of ATP6V1C2 expression in transfected 293T cell line (H00245973-T01) by ATP6V1C2 MaxPab polyclonal antibody.
Lane 1: ATP6V1C2 transfected lysate(43.9 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of ATP6V1C2 transfected lysate using anti-ATP6V1C2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with ATP6V1C2 purified MaxPab mouse polyclonal antibody (B01P) (H00245973-B01P). -
Gene Info — ATP6V1C2
Entrez GeneID
245973GeneBank Accession#
BC012142.1Protein Accession#
AAH12142.1Gene Name
ATP6V1C2
Gene Alias
ATP6C2, VMA5
Gene Description
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
Gene Ontology
HyperlinkGene Summary
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms. [provided by RefSeq
Other Designations
ATPase, H+ transporting, lysosomal 42kD, V1 subunit C|OTTHUMP00000115522|V-ATPase C2 subunit|vacuolar H+ ATPase C2
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Interactome
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Disease
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