ATP6V0D2 monoclonal antibody (M01), clone 7A4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ATP6V0D2.
Immunogen
ATP6V0D2 (NP_689778, 238 a.a. ~ 306 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ETLYPTFGKLYPEGLRLLAQAEDFDQMKNVADHYGVYKPLFEAVGGSGGKTLEDVFYEREVQMNVLAFN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93); Rat (92)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33.33 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ATP6V0D2 is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — ATP6V0D2
Entrez GeneID
245972GeneBank Accession#
NM_152565Protein Accession#
NP_689778Gene Name
ATP6V0D2
Gene Alias
ATP6D2, FLJ38708, VMA6
Gene Description
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
Gene Ontology
HyperlinkGene Summary
ATPase
Other Designations
ATPase, H+ transporting, lysosomal 38kD, V0 subunit d|ATPase, H+ transporting, lysosomal 38kDa, V0 subunit D2
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Interactome
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Pathway
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Publication Reference
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Bovine parathyroid hormone enhances osteoclast bone resorption by modulating V-ATPase through PTH1R.
Liu S, Zhu W, Li S, Ma J, Zhang H, Li Z, Zhang L, Zhang B, Li Z, Liang X, Shi W.
International Journal Of Molecular Medicine 2016 Feb; 37(2):284.
Application:WB-Ce, Mouse, Osteoclast(monocyte-macrophage).
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Increased IL-6 expression in osteoclasts is necessary but not sufficient for the development of Paget's disease of bone.
Teramachi J, Zhou H, Subler MA, Kitagawa Y, Galson DL, Dempster DW, Windle JJ, Kurihara N, Roodman GD.
Journal of Bone and Mineral Research 2014 Jun; 29(6):1456.
Application:WB-Ce, Mouse, Osteoclasts.
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Bovine parathyroid hormone enhances osteoclast bone resorption by modulating V-ATPase through PTH1R.
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