PI16 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human PI16 full-length ORF ( AAH22399.2, 1 a.a. - 408 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MHGSCSFLMLLLPLLLLLVATTGPVGALTDEEKRLMVELHNLYRAQVSPTASDMLHMRWDEELAAFAKAYARQCVWGHNKERGRRGENLFAITDEGMDVPLAMEEWHHEREHYNLSAATCSPGQMCGHYTQVVWAKTERIGCGSHFCEKLQGVEETNIELLVCNYEPPGNVKGKRPYQEGTPCSQCPSGYHCKNSLCEPIGSPEDAQDLPYLVTEAPSFRATEASDSRKMGTPSSLATGIPAFLVTEVSGSLATKALPAVETQAPTSLATKDPPSMATEAPPCVTTEVPSILAAHSLPSLDEEPVTFPKSTHVPIPKSADKVTDKTKVPSRSPENSLDPKMSLTGARELLPHAQEEAEAEAELPPSSEVLASVFPAQDKPGELQATLDHTGHTSSKSLPKFPQYLCHR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
70.8
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PI16
Entrez GeneID
221476GeneBank Accession#
BC022399.1Protein Accession#
AAH22399.2Gene Name
PI16
Gene Alias
CRISP9, DKFZp586B1817, MGC45378, MSMBBP, PSPBP
Gene Description
peptidase inhibitor 16
Gene Ontology
HyperlinkGene Summary
beta-binding protein|protease inhibitor 16
Other Designations
OTTHUMP00000016309|PSP94-binding protein|microseminoprotein, beta-binding protein|protease inhibitor 16
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Interactome
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Publication Reference
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Skin-homing CD8+ T cells preferentially express GPI-anchored peptidase inhibitor 16, an inhibitor of cathepsin K.
Lupsa N, Érsek B, Horváth A, Bencsik A, Lajkó E, Silló P, Oszvald Á, Wiener Z, Reményi P, Mikala G, Masszi T, Buzás EI, Pós Z.
European Journal of Immunology 2018 Dec; 48(12):1944.
Application:Func, Human, Human skin samples.
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PI16 is expressed by a subset of human memory Treg with enhanced migration to CCL17 and CCL20.
Nicholson IC, Mavrangelos C, Bird DR, Bresatz-Atkins S, Eastaff-Leung NG, Grose RH, Gundsambuu B, Hill D, Millard DJ, Sadlon TJ, To S, Zola H, Barry SC, Krumbiegel D.
Cellular Immunology 2012 Jan; 275(1-2):12.
Application:Func, Human, Human memory Treg cells.
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Skin-homing CD8+ T cells preferentially express GPI-anchored peptidase inhibitor 16, an inhibitor of cathepsin K.
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